1 edition of Guide to the care and use of experimental animals. found in the catalog.
Includes bibliographies.Volume 1 reprinted 1984 with addendum.
|Statement||Canadian Council on Animal Care|
|Publishers||Canadian Council on Animal Care|
|The Physical Object|
|Pagination||xvi, 109 p. :|
|Number of Pages||80|
nodata File Size: 9MB.
Compounds that do not meet the anticipated level of performance at any stage may result in subsequent rounds of iterative medicinal chemistry to generate improved leads. On-the-job training, supplemented with institution-sponsored discussion and training programs and reference materials applicable to their jobs and the species in their care, should be provided Guide to the care and use of experimental animals. each employee responsible for animal care Kreger 1995.
Where exceptions are required in relation to the provisions of these Principles, the decisions should not rest with the investigators directly concerned but should be made, with due regard to Principle II, by an appropriate review group such as an institutional animal care and use committee. at least one practicing scientist experienced in research involving animals• Unexpected Outcomes Fundamental to scientific inquiry is the investigation of novel experimental variables.
Training strategies for laboratory animal veterinarians: Challenges and opportunities. An illustrative process for tumour model selection and use.
All of the institution's programs and facilities including satellite facilities for activities involving animals have also been evaluated by the IACUC and will be reevaluated by the IACUC at least once every six months, in accordance with IV. Standards for Protection against Radiation. The Guide endorses these concepts as important operating principles for all US and non-US animal care and use programs. Title 29, Part 1910, Occupational Safety and Health Standards, Subpart G, Occupational Health and Environmental Control, and Subpart Z, Toxic and Hazardous Substances.
In the case of conditioned-response research protocols, use of a highly preferred food or fluid as positive reinforcement, instead of restriction, is recommended. Recommendations in the Guide are based on published data, scientific principles, expert opinion, and experience with methods and practices that have proved to be consistent with both high-quality research and humane animal care and use.
National Institutes of Health Office of Laboratory Animal Welfare 2002.
Consultants may not approve or withhold approval of an activity or vote with the IACUC unless they are also members of the IACUC. be authorized to suspend an activity involving animals in accordance with the specifications set forth in IV. The Principles were incorporated into the PHS Policy in 1986 and continue to provide a framework for conducting research in accordance with the Policy. J Appl Anim Welf Sci 6:163-173.
The Committee to Revise the Guide for the Care and Use of Laboratory Animals was appointed in 1993 by the National Research Council; its 15 members included research scientists, veterinarians, and nonscientists representing bioethics and the public's interest in animal welfare.
The regulation process may entail scheduled access to food or fluid sources, so an animal consumes as much as desired at regular intervals, or restriction, in which the total volume of food or fluid consumed is strictly monitored and controlled NRC 2003b.